GO model-based gene set analysis (MGSA) [25] using the Ontologizer [65].

For the analysis, 2,142 genes with significantly higher expression in the neo aortic samples and 1,327 genes with significantly higher expression in the w6 aortic samples were compared to all 27,827 genes represented on the microarray. Study count and population count indicate the number of genes in the study sets of differentially regulated genes and the population set of all genes on the microarray that are annotated to the GO term in question. Terms with marginal probabilities higher than 0.5 are more likely than not to be related to the observed profile of differential expression [25].