MAP4K4 in complex with inhibitor GNE-495
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MAP4K4 in complex with inhibitor GNE-495 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 8-amino-N-[1-(cyclopropylcarbonyl)azetidin-3-yl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide, MAGNESIUM ION, ... Authors: Harris, S.F, Wu, P, Coons, M. Deposit date: 2015-04-29 Release date: 2015-09-02 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis. Acs Med.Chem.Lett., 6, 2015
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2015-04-29
