Comparing populations of benign nuclei from negative biopsies in a case-control study: subsequent diagnosis of prostate cancer is associated with a “cancer-like” nuclear morphometric score* (MFSp). Scores derived from external datasets.

*Model A: 5 features selected by backwards elimination (FeretY_ave, MaxDiameter_ave, Elongation_ave, Slope_ave and ODKurtosis_ave).**Model B: 5 features (SumOD_sd, MaxDiam_sd, TSD_sd, TEntropy_sd, No.MedDensityObjects_sd), selected after competition among all models with ≤5 covariates based on leave-one-out AUC.