Super enhancers orchestrate osteogenesis program through navigation and initiation effects of Brd4 on Zbtb16 [CUT&TAG]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206155
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We performed multiomic high-throughput sequencing to recapitulated the primary mechanism of mesenchymal stem cells osteogenesis. We analysed the H3K27ac ChIP-seq, BRD4 CUT&Tag and RNA-seq data before and after osteogenesis, and identified super enhancers (SEs) regulated osteogenic identity genes in MSCs. Examination of the BRD4 binding to genome in MSCs
创建时间：
2023-05-12
