The 31 sequelae (categorized as either reversible or irreversible) and associated mortality in the Global Burden of Disease 2010 study for the ten London Declaration NTDs, except Guinea worm.

The bold numbers reflect the years lived with disability (YLD) and years of life lost (YLL) for each NTD in 2010, as estimated by the GBD 2010 study [1–4]. The excess mortality rate (μ*) was chosen to reflect the severity of the sequela. The average disability weights were used to relate YLD to prevalent cases in our calculations for NTDs with multiple sequelae. Salomon et al. [24] provide more information about disability weights and lay explanations of sequelae. (a) The original GBD value for LF was 2.74 million YLD, but as Cambodia, Federated States of Micronesia, Maldives, Samoa, Sri Lanka, Togo, Tonga, Vanuatu, and Vietnam had reached elimination before 2010, their remaining burden (total of 0.04 million YLD) was removed from our calculations. (b) The GBD values for leprosy were based on a recalculation; see methods section. (c) A disability weight (DW = 0.097) for visceral leishmaniasis was needed to distinguish it from cutaneous leishmaniasis (DW = 0.013), as both were combined as leishmaniasis in the YLD values available from GBD; YLL due to leishmaniasis was assumed to be fully caused by visceral leishmaniasis.