Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea
收藏Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Kadcoccitones_A_and_B_Two_New_6_6_5_5_Fused_Tetracyclic_Triterpenoids_from_i_Kadsura_coccinea_i_/2458780
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资源简介：
A pair of new triterpenoid epimers, kadcoccitones A (1) and B (2), together with a new biogenetically related compound kadcoccitone C (3), were isolated from Kadsura coccinea. The epimers featured an unprecedented carbon skeleton with a 6/6/5/5-fused tetracyclic ring system unit and a C9 side chain. Their structures were determined by spectroscopic data, ECD calculation, and single-crystal X-ray diffraction. Compounds 1 and 3 showed anti-HIV-1 activity with an EC50 value of 47.91 and 32.66 μg/mL, respectively.
创建时间：
2016-02-20
