Transcriptome sequencing data analysis of Bacillus subtilis NCIB 3610 treated with DMSO and AQCA

In our study, we discovered that AQCA (Anthraquinone-2-carboxylic acid) effectively degrades Bacillus subtilis NCIB 3610 biofilms, a finding of significant research importance. To investigate the underlying mechanisms, we performed transcriptome sequencing of wild-type biofilms treated with either DMSO (control) or AQCA. Statistical analysis of gene expression (P < 0.05) revealed that AQCA treatment led to significant changes: 184 genes were upregulated, while 503 genes were downregulated by at least twofold compared to the DMSO control group. mRNA profiles of Bacillus subtilis NCIB 3610 wild type biofilms treated with DMSO and AQCA