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Environmental aromatic amine induces pulmonary arterial hypertension associated with estrogen signaling and Serpine1

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE287019
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We examined the molecular pathways underlying the DAPM-induced pulmonary arterial hypertension in intact and ovariectomized female rats. 11-15 week old female (intact and ovariectomized) Sprague-Dawley rats were treated with vehicle (35% ethanol) and 25mg/kg DAPM orally once weekly for 12 weeks.
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2025-04-01
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