Neurofilament-light chain (NF-L) is a well-known clinical biomarker of many neurodegenerative diseases. By analyzing amyotrophic lateral sclerosis (ALS) patients cerebrospinal fluid (CSF) or plasma, p
INTRODUCTION: Huntington’s disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive, and psychiatric decline. The Unified Huntington’s Disease Rating Scale Total Moto
Histone H3K9 methylated heterochromatin silences repetitive non-coding sequences and lineage-specific genes during development, but how tissue-specific genes escape from heterochromatin in differentia
Additional file 5. Ingenuity Pathway Analysis (IPA) of genes differentially expressed in forebrain /midbrain (F/M) and cerebellum (Cb) in Tpp1−/− mouse brains versus control brains at 1-, 2- and 3- an