Crystal structure of CRAF/MEK1 complex with NST-628 and inactive RAF
收藏Protein Data Bank Japan2024-07-10 更新2026-04-19 收录
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Crystal structure of CRAF/MEK1 complex with NST-628 and inactive RAF Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Dual specificity mitogen-activated protein kinase kinase 1, ... Authors: Quade, B, Huang, X. Deposit date: 2024-03-07 Release date: 2024-04-17 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (2.41 Å) Cite: The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers. Cancer Discov, 14, 2024
创建时间：
2024-03-07
