Mechanical Memory Primes Cells for Confined Migration via NFATC2 Signaling
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP584053
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资源简介：
Cells retain a memory of past mechanical environments, influencing their future behavior. This project investigates how mechanical memory affects cell morphology and migration, especially under confinement, using human cell lines (MDA-MB-231, HT1080, HFF-1) exposed to soft (1 kPa), stiff (34 kPa), and rigid (glass) substrates for 7 days. Through transcriptomic profiling (RNA-seq), we identify NFATC2 as a key regulator of this memory effect.
创建时间：
2026-03-08
