DIP-chip: Rapid and accurate determination of DNA-binding specificity
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Validation of DNA ImmunoPrecipitation with microarray analysis (DIP-chip) technique using the Leu3 DNA binding domain.
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相关数据集
The Regulatory Specificity of a Homeodomain Protein is Determined by Unique DNA-Binding Sequences. Drosophila melanogaster
Homeodomain (HD) proteins comprise a large family of evolutionarily conserved transcription factors (TFs) having diverse developmental functions, yet they paradoxically recognize very similar DNA sequ
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Divergence in DNA specificity among paralogous transcription factors contributes to their differential in vivo binding [RG_MycMaxMad_v1]
Members of transcription factor (TF) families, i.e. paralogous TFs, are oftentimes reported to have identical DNA-binding motifs, despite the fact that they perform distinct regulatory functions in th
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Diverse CGG binding proteins across eukaryotes produced by independent domestications of hAT transposons. Diverse CGG binding proteins across eukaryotes produced by independent domestications of hAT transposons
The human transcription factor (TF) CGGBP1 (“CGG Binding Protein”) is conserved only in amniotes, and is believed to derive from the zf-BED and Hermes transposase DNA-binding domains (DBDs) of a hAT D
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MSL2 reads DNA shape to distinguish X from autosome for dosage compensation (SXL RNAi in Kc cells experiments). Drosophila melanogaster
The rules according to which transcription factors selectively bind only a small subset of genomic sites from a vast pool of similar sequences are not understood. One of the most challenging tasks in
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Computational design of sequence-specific DNA-binding proteins
Sequence-specific DNA-binding proteins (DBPs) play critical roles in biology and biotechnology, and there has been considerable interest in the engineering of DBPs with new or altered specificities fo
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