CryoEM structure of P-Glycoprotein in inward facing 1 state under continuous turnover conditions with vinblastine
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CryoEM structure of P-Glycoprotein in inward facing 1 state under continuous turnover conditions with vinblastine Descriptor: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent translocase ABCB1, ... Authors: Culbertson, A, Liao, M. Deposit date: 2023-04-02 Release date: 2025-04-23 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Cryo-EM of human P-glycoprotein reveals an intermediate occluded conformation during active drug transport. Nat Commun, 16, 2025
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2023-04-02
