During cancer development and progression massive alterations in gene expression have been observed. The regulation of genes occurs within the context of the 3D genome. However, the impact of disease
We used gene expression profiling of human DCIS and IBC to discover uniquely expressed genes that may also regulate progression. Overall design: RNA from human samples were extracted, purified, amplif
Purpose: The goal of the study is to compare NGS-derived transcriptome in an isogenic breast cancer progression model cell line system. By comparing the protein-coding and noncoding gene expression of
Breast cancer consists of at least five main molecular “intrinsic” subtypes, which are reflected in both pre-invasive and invasive disease. Although previous studies have suggested that many of the mo