Gene expression profiles of colorectal cancer tissues and tumor-adjacant tissues reveal key genes that participate in oncogenic activities

To investigate the key genes involved in the inception and progression of colorectal cancer, we obtained tumor and tumor-adjacant tissues from CRC patients who underwent surgical resection and sent them to high-throughput sequencing. In this study, we compared the gene expression profiles of tumor tissues and normal tissues, aiming at identifying differentially expressed genes. Our study revealed a set of differentially expressed genes that may participate in the oncogenic activities during CRC inception and development. We sequenced RNA from the colorectal cancer tissues and normal tissues of two patients. Two replicates per sample were included