Antioxidant, anti-inflammatory and improving intestinal flora of Forsythia suspensa leaf fermented tea extract

The aim was to establish a theoretical foundation for the functional study of Forsythia suspensa leaf and provide specific recommendations for their growth and application. The results showed that H2O2 led to an increase in oxidative levels in mice, and Forsythia suspensa leaf fermented tea had been shown to have antioxidant effects via the Ref-1/HIF-1α pathway, reduce inflammation caused by hydrogen peroxide through the TLR4/NF-κB signaling pathway and protect mice's colons from oxidative stress by repairing gut microbiota imbalance and increasing microbial diversity and abundance. These findings have established a theoretical basis for studying the functional properties of Forsythia suspensa leaf fermented tea.