Crystal structure of FnCas12a in complex with pre-crRNA and 12nt target DNA

Crystal structure of FnCas12a in complex with pre-crRNA and 12nt target DNA Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*AP*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*AP*GP*GP*AP*CP*T)-3'), DNA (5'-D(P*AP*GP*TP*CP*CP*TP*TP*TP*AP*GP*AP*TP*A)-3'), ... Authors: Lin, X, Chen, J, Liu, L. Deposit date: 2024-01-22 Release date: 2025-01-01 Last modified: 2025-02-19 Method: X-RAY DIFFRACTION (2.3 Å) Cite: DNA target binding-induced pre-crRNA processing in type II and V CRISPR-Cas systems. Nucleic Acids Res., 53, 2025