five

Structure of the human GluN1/GluN2A LBD in complex with compound 9 (GNE3500)

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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Structure of the human GluN1/GluN2A LBD in complex with compound 9 (GNE3500) Descriptor: (1R,2R)-2-(2-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-6-yl)cyclopropane-1-carbonitrile, GLUTAMIC ACID, GLYCINE, ... Authors: Wallweber, H.J.A, Lupardus, P.J. Deposit date: 2016-10-20 Release date: 2016-11-30 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.48 Å) Cite: GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett, 8, 2017
创建时间:
2016-10-20
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