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Lipids and Neurotransmitters Mass Spectrometry Imaging Data from Dopaminergic PSAP Deficient (cPSAPDAT) and Serotonergic PSAP deficient (cPSAPSERT) Mice Brain Tissue sections

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figshare.scilifelab.se2023-08-11 更新2025-03-26 收录
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https://figshare.scilifelab.se/articles/dataset/Lipids_and_Neurotransmitters_Mass_Spectrometry_Imaging_Data_from_Dopaminergic_PSAP_Deficient_cPSAP_sup_DAT_sup_and_Serotonergic_PSAP_deficient_cPSAP_sup_SERT_sup_Mice_Brain_Tissue_sections/23856609/1
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The files above are MALDI-MSI (Matrix Assisted Laser Desorption Ionization - Mass Spectrometry Imaging) experiments. The dataset contains both imzML, which is the common MSI open file type containing x, y positions in tissue as well as m/z and intensity, which is a more user friendly format. The data contained in this dataset should be enough to recreate the MSI parts of the manuscript. Prosaposin (PSAP) modulates glycosphingolipid metabolism and may relate to Parkinson’s disease (PD). Here, the lipids and neurotransmitters MALDI-MSI data have been collected from dopaminergic PSAP-deficient (cPSAPDAT) mice and serotonergic PSAP-deficient (cPSAPSERT) mice as well as 6-OHDA-induced Parkinson's disease mouse model.For any questions about the dataset or to request access to any files not uploaded here, please contact per.andren@uu.se

上述文件包含了基质辅助激光解吸电离-质谱成像(MALDI-MSI)实验数据。该数据集包含了imzML格式,这是一种通用的MSI开放文件格式,其中包含组织中的x、y坐标以及m/z和强度值,同时提供了更为用户友好的格式。该数据集内含的数据足以复现文献中的MSI部分。Prosaposin(PSAP)调节糖基鞘脂质代谢,可能与帕金森病(PD)有关。在此,我们收集了多巴胺能PSAP缺陷型(cPSAPDAT)小鼠和血清素能PSAP缺陷型(cPSAPSERT)小鼠,以及由6-OHDA诱导的帕金森病小鼠模型中的脂质和神经递质MALDI-MSI数据。如对数据集有任何疑问或需要访问未上传的文件,请联系per.andren@uu.se。
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