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Generation of ventralized thalamic organoids with inhibitory thalamic reticular nucleus

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NIAID Data Ecosystem2026-05-01 收录
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Single-cell RNA-seq was performed in SHH-treated thalamic organoids Human thalamic organoids (ThOs) resembling the dorsal thalamus by dual SMAD inhibition and insulin-driven caudalization coupled with thalamic patterning (MEK-ERK inhibition and BMP7 activation) from hESCs. The organoids were further guided into ventral identity with SHH treatment.

创建时间:
2023-04-25
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