five

wound healing

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The aim of this study was to evaluate the effectiveness of Persian oak aqueous extract on dermal wound healing in rats. 35 male Wistar rats were selected and randomly divided into five groups; then two full-thickness wounds with 10 mm in diameter were created bilaterally on the back of all animals. Negative control group treated with normal saline, positive control group treated with phenytoin cream, and three treatment groups which received 2%, 4% and 8% aqueous extract of Jaft respectively. The animals received these medicines once daily for 15 days. The state of the wound healing was evaluated using wound closure ratio, wound contraction and re-epithelialization, tensile strength, VEGF and PDGF content. Histopathological examination was also performed on repaired tissues.
创建时间:
2020-11-01
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