The gene expression in the skeletal muscle affected by TBP-2/Txnip deficiency

To investigate how TBP-2/Txnip regulates insulin sensitivity in the skeletal muscle, we performed microarray analyses. The gene expression in the skeletal muscle from WT, TBP-2-/-, ob/ob, ob/ob TBP-2-/- at 10 weeks age were performed.为探究TBP-2/Txnip如何调控骨骼肌的胰岛素敏感性，我们开展了基因芯片（microarray）分析。本次实验采集了10周龄的野生型（Wild Type, WT）、TBP-2基因敲除（TBP-2-/-）、ob/ob及ob/ob TBP-2-/-小鼠的骨骼肌样本，对其基因表达水平进行了检测。