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Glucocerebrosidase in complex with pharmacological chaperone IMX8

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6q1n
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Glucocerebrosidase in complex with pharmacological chaperone IMX8 Descriptor: (2R,3S,4S,5R)-2-[2-(methylsulfanyl)ethyl]piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Vickers, C, Withers, S.G, Boraston, A.B. Deposit date: 2019-08-05 Release date: 2020-08-19 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.526 Å) Cite: Pharmacological chaperones for GCase that switch conformation with pH enhance enzyme levels in Gaucher animal models. To Be Published
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2019-08-05
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