PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1

Active PI3K in complex with phosphorylated ERBB2:ERBB4cyt1 heterodimer phosphorylates PIP2 into PIP3, leading to activation of AKT signaling.

活性PI3K与磷酸化ERBB2:ERBB4cyt1异源二聚体相互作用，导致PI2磷酸化为PI3，进而激活AKT信号通路。