Crystal structure of human CDK2 complexed with a pyrazolo[1,5-a]pyrimidine inhibitor
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Crystal structure of human CDK2 complexed with a pyrazolo[1,5-a]pyrimidine inhibitor Descriptor: (5-CHLOROPYRAZOLO[1,5-A]PYRIMIDIN-7-YL)-(4-METHANESULFONYLPHENYL)AMINE, Cell division protein kinase 2 Authors: Williamson, D.S, Parratt, M.J, Torrance, C.J, Bower, J.F, Moore, J.D, Richardson, C.M, Dokurno, P, Cansfield, A.D, Francis, G.L, Hebdon, R.J, Howes, R, Jackson, P.S, Lockie, A.M, Murray, J.B, Nunns, C.L, Powles, J, Robertson, A, Surgenor, A.E. Deposit date: 2004-12-14 Release date: 2005-02-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.996 Å) Cite: Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2. Bioorg.Med.Chem.Lett., 15, 2005
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2004-12-14
