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Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE44583
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Global analyses of two prototypical SR proteins (SRFS1 and SFRS2 using splicing-sensitive arrays and CLIP-seq on mouse embryo fibroblasts carrying tet-repressible versions of the two genes. 4 biological replicate sets of SFRS1 or SFRS2 tet-repressible MEFs were grown for 5 days -/+ docycline. Total RNA was isolated and labeled targets hybridized to Affymetrix mouse splicing arrays. This is the gene expression component of the study only.
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2013-04-12
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