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资源简介：
recombinant yeast population designed for mapping mitonuclear interactions
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创建时间：
2023-03-21
相关数据集
Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome
Mitochondrial DNA copy number (mtDNA-CN) is associated with several age-related chronic diseases and is a predictor of all-cause mortality. Here, we examine site-specific differential nuclear DNA (nDN
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Mitonuclear effects on sex ratio persist across generations in interpopulation hybrids
Eukaryotic energy production requires tight coordination between nuclear and mitochondrial gene products. Because males and females often have different energetic strategies, optimal mitonuclear coord
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Mitochondrial DNA background significantly alters transcriptional response to a various diets in mice. Mus musculus
Mutations in the mitochondrial DNA (mtDNA) have been proposed to be essential for metabolic adaptation, and because metabolism is intrinsically associated with multiple disease states, including obesi
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Mitonuclear interactions and early-life diet shape adult nutritional behaviour
Mitochondrial function relies on close coordination between the mitochondrial and nuclear genomes. Disruption to this coordinationâvia mitonuclear mismatchâcan impair metabolic efficiency, particu
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Nuclear-mitochondrial genetic mismatch elicits an interferon-mediated cellular immune response
In this study, we used mRNA-Seq and functional assays to investigate the transcriptomic and cellular responses to nuclear-mitochondrial genetic mismatches using the xenomitochondrial cybrid panel. RNA
NIAID Data Ecosystem30
