Co-Structure of SARS-CoV-2 3C-like proteinase nsp5 with Compound 34
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Co-Structure of SARS-CoV-2 3C-like proteinase nsp5 with Compound 34 Descriptor: (4S)-4-(iminomethyl)-3-(isoquinolin-4-yl)-1-[(1s,3R)-3-(trifluoromethyl)cyclobutyl]imidazolidin-2-one, 3C-like proteinase nsp5 Authors: Knapp, M.S, Ornelas, E. Deposit date: 2025-04-22 Release date: 2026-03-04 Last modified: 2026-04-15 Method: X-RAY DIFFRACTION (1.871 Å) Cite: Discovery of EGT710, an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor. J.Med.Chem., 69, 2026
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2025-04-22
