Swainsonine induces liver inflammation in mice via gut-liver axis

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肝脏炎症

肠-肝轴

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA861701 数据链接链接失效反馈

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Swainsonine induces liver inflammation in mice via gut-liver axis

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2022-07-23

Notch signaling regulates macrophage-mediated inflammation in non-alcoholic steatohepatitis

肝脏炎症

巨噬细胞分化

The liver macrophage population comprises resident Kupffer cells (KCs) and recruited monocyte-derived macrophages. Monocytes are mostly recruited during liver inflammation and can differentiate into s

DataCite Commons2025-06-01 更新780

Intestinal Activation of Notch Signaling Induces Rapid Onset Hepatic Steatosis and Insulin Resistance

非酒精性脂肪肝病

肠-肝轴

Here we investigate the effects of expressing an activated mutant of Notch (ICD-E) in an inducible transgenic mouse model. Hepatic expression of ICD-E in adult animals has no detectable phenotype, but

NIAID Data Ecosystem60

DataSheet_1_IL-2 availability regulates the tissue specific phenotype of murine intra-hepatic Tregs.docx

免疫调节

肝脏炎症

CD4+CD25+Foxp3+ Tregs are known to acquire tissue-specific features and exert cytoprotective and regenerative functions. The extent to which this applies to liver-resident Tregs is unknown. In this st

NIAID Data Ecosystem50

Hepatic fibrosis in correlation to hepatic inflammation.

肝脏纤维化

肝脏炎症

Hepatic fibrosis in correlation to hepatic inflammation.

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Table_1_Epigenetic Regulation of Hepatic Stellate Cell Activation and Macrophage in Chronic Liver Inflammation.DOC

肝脏炎症

表观遗传学

Chronic liver inflammation is a complex pathological process under different stress conditions, and the roles of stellate cells and macrophages in chronic liver inflammation have been widely reported.

NIAID Data Ecosystem50

Swainsonine induces liver inflammation in mice via gut-liver axis

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