Expression data from SOX9 overexpressing EndoC-ßH1 cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE104195
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资源简介：
Human ß cell dedifferentiation as a potent mechanism of diabetes is gaining prominence. Several data suggest an upregulation of the transcription factor SOX9, a progenitor and duct cell marker during ß cell dedifferentiation. However, its targets in such cells need more understanding. Here, we overexpressed SOX9 and a constitutively active mutant (VP16-SOX9∆TAD) in Human pancreatic beta EndoC-ßH1 cells in order to understand its targets. EndoC-ßH1 cells were transfected with either MCS-ires-GFP, VP16-ires-GFP, SOX9WT-ires-GFP or VP16-SOX9∆TAD-ires-GFP and FAC sorted 48h post transfection for RNA extraction and hybridization on Affymetrix microarrays
创建时间：
2021-07-25
