The 1.63A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5524529
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The 1.63A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5524529 Descriptor: E3 ubiquitin-protein ligase Mdm2, SULFATE ION, [(4S,5R)-4,5-bis(4-chlorophenyl)-2,4,5-trimethyl-4,5-dihydro-1H-imidazol-1-yl]{4-[3-(methylsulfonyl)propyl]piperazin-1-yl}methanone Authors: Janson, C, Lukacs, C, Graves, B. Deposit date: 2013-02-13 Release date: 2013-08-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor. ACS Med Chem Lett, 4, 2013
创建时间:
2013-02-13



