mRNA-seq of satellite cells cultured and expanded in F10 conventional medium, T cell conditional medium, and cytokine cocktail
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=8297765d463d69eff8ee744eed47ff33
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资源简介：
Like most adult stem cells, culturing and expansion of satellite cells (muscle stem cells) are difficult, that prevents the utilization of satellite cells in cell-based therapies. Here, we reveal that T cells infiltrated into the injury site upon acute inflammation are able to promote muscle stem cell proliferation, expansion, and maintain their injury reparation abilities in vivo. Four cytokines, IL-1α, IL-13, TNF-α, and IFN-γ, were identified as the effective components secreted by T cells to faciliate satellite cell propagation
提供机构：
Shanghai Institute of Biochemistry and Cell Biology
创建时间：
2022-02-20
