Single-Cell RNA Sequencing of PBMCs from Clinically Stable Connective Tissue Disease-associated Interstitial Lung Disease (CTD-ILD) Patients after Lung Transplantation

Connective tissue disease-associated interstitial lung disease (CTD-ILD) is a major indication for lung transplantation in patients with advanced disease. Here, we performed single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) from two clinically stable CTD-ILD patients after lung transplantation to characterize circulating immune cell populations and their transcriptional profiles. This dataset provides a single-cell transcriptomic resource for investigating immune heterogeneity and systemic immune status in CTD-ILD patients following lung transplantation.