Aedes albopictus immune responses to chikungunya virus infection

In this study, aimed at understanding the molecular interactions between Ae. albopictus and CHIKV, we analyzed by RNAseq CHIKV-infected and uninfected control mosquitoes. We focused our attention on key mosquito organs at one- and five-days post-blood meal ingestion, which correspond to viral entry and dissemination, and found specific transcriptional changes involving various pathways during the CHIKV lifecycle.