Catalytic Direct α‑Amination of Arylacetic Acid Synthons with Anilines
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https://figshare.com/articles/dataset/Catalytic_Direct_Amination_of_Arylacetic_Acid_Synthons_with_Anilines/13031082
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资源简介：
A unique α-amination approach
using various anilines has
been developed for arylacetic acids via adaptation as benzazoles.
The reaction proceeds through a single electron transfer mechanism
utilizing an iron-based catalyst system to access α-(N-arylamino)acetic acid equivalents. Modification of approved
drugs, facile cleavage of the benzazole auxiliary, and tolerance of
amide linkage forming conditions constitute the potential applicability
of this strategy.
创建时间：
2020-09-30
