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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64)

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) Descriptor: Plasminogen activator inhibitor 1, VHH-2g-42, VHH-2w-64 Authors: Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. Deposit date: 2018-06-25 Release date: 2020-01-01 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020
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2018-06-25
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