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Homo- and hetero-dimeric subunit interactions set affinity and efficacy in metabotropic glutamate receptors

NIAID Data Ecosystem2026-05-01 收录

数据链接：

https://figshare.com/articles/dataset/Homo-_and_hetero-dimeric_subunit_interactions_set_affinity_and_efficacy_in_metabotropic_glutamate_receptors/22720387 数据链接链接失效反馈

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资源简介：

single molecule analysis of GPCRs

应用场景：

创建时间：

2023-12-14

蛋白质结构解析

代谢型谷氨酸受体

Cryo-EM structure of inactive mGlu7 homodimer Descriptor: Isoform 3 of Metabotropic glutamate receptor 7 Authors: Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. Deposit date:

Protein Data Bank Japan2024-11-06 更新60

Structural basis of class C metabotropic glutamate receptor signal transduction

C类GPCR结构解析

代谢型谷氨酸受体

Metabotropic glutamate receptors (mGluR) are Class C GPCRs. They are obligate dimers, dimerization being fundamental for their function. mGluRs are activated by the binding of the main excitatory neur

ESRF Portal2026-01-01 更新20

Crystal structure of the ligand-binding region of the group III metabotropic glutamate receptor

代谢型谷氨酸受体

X-射线衍射

Crystal structure of the ligand-binding region of the group III metabotropic glutamate receptor Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Metabotropic glutamate receptor 7 Authors: Muto, T, Ts

Protein Data Bank Japan2024-10-23 更新20

Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant

GPCR晶体结构解析

代谢型谷氨酸受体

Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACI

Protein Data Bank Japan2023-09-20 更新40

Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with 1S,3S-ACPD

代谢型谷氨酸受体

蛋白质-配体相互作用

Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with 1S,3S-ACPD Descriptor: (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid, 2-acetamido-2-deo

Protein Data Bank Japan2024-10-23 更新20

Homo- and hetero-dimeric subunit interactions set affinity and efficacy in metabotropic glutamate receptors

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