five

SARS-CoV-2 Mpro in complex with compound 7

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Protein Data Bank Japan2025-08-06 更新2026-04-04 收录
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https://pdbj.org/mine/summary/9du2
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SARS-CoV-2 Mpro in complex with compound 7 Descriptor: 3C-like proteinase nsp5, N-[(2S)-3-cyclopropyl-1-{[(1Z,2S)-1-imino-4-(methanesulfonyl)butan-2-yl]amino}-1-oxopropan-2-yl]-4-methoxy-1H-indole-2-carboxamide Authors: Bigelow, L, Tang, H, Boguslaw, N, Duda, D.M. Deposit date: 2024-10-02 Release date: 2025-04-30 Last modified: 2025-08-06 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Inhibition of dimeric SARS-CoV-2 Mpro displays positive cooperativity and a mixture of covalent and non-covalent binding. Iscience, 28, 2025
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2024-10-02
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