Distinct SARS-CoV-2 sensing pathways in pDCs driving TLR7-antiviral vs. TLR2-immunopathological responses in COVID-19
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE195894
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In this study, we broadly investigated the nature and timing of SARS-CoV-2-induced changes in pDC gene expression, therefore we profiled 789 selected genes using NanoString nCounter technology after 4, 24 and 48 hrs in two individual donors found to be high (Dhigh) and low (Dlow) responders in terms of IFN production Total RNA was purified from pDC cells from two individual donors infected with SARS-CoV-2 after 4, 24 and 48 hrs
创建时间：
2022-05-26
