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Transcriptome analysis in primary fibroblasts from HOIL-1-deficient patients upon TNF-α or IL-1β stimulation

ChEBI2012-10-28 更新2026-07-21 收录

遗传性免疫缺陷机制

炎症反应转录组

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40560 数据链接链接失效反馈

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资源简介：

Transcriptome analysis in primary fibroblasts from HOIL-1-deficient patients upon TNF-α or IL-1β stimulation

应用场景：

创建时间：

2012-10-28

表观遗传调控

炎症反应转录组

Complex organisms are able to rapidly induce select genes among thousands in response to diverse environmental cues. This occurs in the context of large genomes condensed with histone proteins into ch

NIAID Data Ecosystem70

Expression from Slamonella Typhimurium infected murine peritoneal macrophages

宿主-病原体相互作用

炎症反应转录组

Infection of macrophages by Salmonella induces a transcriptional inflammatory response. The pattern of Salmonella induced genes is significantly altered by the expression of type I interferons. We use

NIAID Data Ecosystem50

Chemical inhibition of APE1 redox and DNA repair functions affects the inflammatory response via different but overlapping mechanisms.

炎症反应转录组

APE1功能研究

The presence of oxidized DNA lesions, such as 7,8-dihydro-8-oxoguanine (8-oxoG) and apurinic/apyrimidinic sites (AP sites), has been described as epigenetic signals that are involved in gene expressio

NIAID Data Ecosystem40

Human CD34+ cells with and without interferon gamma exposure

炎症反应转录组

造血干细胞调控

In order to understand the gene expression pathways affected by inflammation through interferon gamma, total RNA was extracted from human CD34+ cells with and without interferon gamma exposure for 48

NIAID Data Ecosystem60

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity through a pathogenic lipid metabolism-mTOR circuit

遗传性免疫缺陷机制

脂质代谢-mTOR信号通路

Mendelian diseases that present with immune-mediated disorders can provide insights into the molecular mechanisms that drive inflammation. Hermansky-Pudlak syndrome (HPS) types 1 and 4 are caused by d

NIAID Data Ecosystem40

Transcriptome analysis in primary fibroblasts from HOIL-1-deficient patients upon TNF-α or IL-1β stimulation

资源简介：

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