Table2_Clinical profiling of specific diagnostic subgroups of women with chronic pelvic pain.docx

IntroductionChronic pelvic pain (CPP) is a common condition affecting up to 26.6% of women, with many suffering for several years before diagnosis and/or treatment. Its clinical presentation is varied and there are frequently comorbid conditions both within and outside the pelvis. We aim to explore whether specific subgroups of women with CPP report different clinical symptoms and differing impact of pain on their quality of life (QoL).MethodsThe study is part of the Translational Research in Pelvic Pain (TRiPP) project which is a cross-sectional observational cohort study. The study includes 769 female participants of reproductive age who completed an extensive set of questions derived from standardised WERF EPHect questionnaires. Within this population we defined a control group (reporting no pelvic pain, no bladder pain syndrome, and no endometriosis diagnosis, N = 230) and four pain groups: endometriosis-associated pain (EAP, N = 237), interstitial cystitis/bladder pain syndrome (BPS, N = 72), comorbid endometriosis-associated pain and BPS (EABP, N = 120), and pelvic pain only (PP, N = 127).ResultsClinical profiles of women with CPP (13–50 years old) show variability of clinical symptoms. The EAP and EABP groups scored higher than the PP group (p

慢性盆腔痛（CPP）是一种普遍影响高达26.6%女性的疾病，许多患者在确诊和治疗之前会遭受数年的痛苦。其临床表现为多样性，且盆腔内外常伴随有其他合并症。本研究旨在探讨具有CPP的女性特定亚组是否报告了不同的临床症状，以及疼痛对其生活质量（QoL）的影响是否存在差异。研究方法：本研究属于盆腔疼痛转化研究（TRiPP）项目的一部分，该项目是一项横断面观察性队列研究。研究纳入了769名育龄女性参与者，她们完成了一系列基于标准化WERF EPHect问卷的广泛问题。在此人群中，我们定义了一个对照组（无盆腔痛、无膀胱疼痛综合征、无子宫内膜异位症诊断，N=230）和四个疼痛组：子宫内膜异位症相关疼痛（EAP，N=237）、间质性膀胱炎/膀胱疼痛综合征（BPS，N=72）、合并子宫内膜异位症相关疼痛和BPS（EABP，N=120）以及仅盆腔痛（PP，N=127）。研究结果：CPP女性（13-50岁）的临床症状表现存在差异。EAP和EABP组的得分高于PP组（p