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Inhibition of human CYP11B1 and CYP11B2 by references <b>I</b>–<b>III</b> and compounds <b>1</b>–<b>21</b>.

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[a]Hamster fibroblasts expressing human CYP11B1 or CYP11B2, respectively; substrate: deoxycorticosterone, 100 nM. [b]SF: selectivity factor = IC50 CYP11B1/IC50 CYP11B2. [c]Fad: fadrozole; nd: not determined.

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2012-11-01
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