Additional file 3: Table S1. of Characterisation of the global transcriptional response to heat shock and the impact of individual genetic variation

Differentially expressed genes following heat shock. Differentially expressed genes for a panel of 43 LCLs exposed to heat shock (42 °C for 1 h, 6 h recovery) and assayed by microarray are shown following limma analysis (FC >1.2, FDR 1.2, FDR <0.01) following heat shock. Table S5. Genes with newly established links to heat shock response. Genes listed together with FC and FDR following heat shock, and p value for presence of the heat shock binding motif. Table S6. Summary of HSF-binding evidence for the promoters of novel and established heat shock response genes. Presence of ChIP-seq peak for HSF1 or HSF2 and HSF1 motif indicated in relation to heat shock genes. Table S7. Differential gene expression between PLS clusters. Differential gene expression between samples assigned to PLS cluster 1 and 2 as assessed by limma analysis is shown for all assayed probes. Table S8. GO categories enriched for genes with increased expression in cluster 2. GO categories for genes differentially expressed between PLS clusters. Categories enriched for genes with increased expression in cluster 2 are shown. Numbers of significant and expected genes shown, together with p values (Fisher’s exact test). Table S9. GO categories enriched for genes with increased expression in cluster 1. GO categories for genes differentially expressed between PLS clusters. Categories enriched for genes with increased expression in cluster 1 are shown. Numbers of significant and expected genes shown, together with p values (Fisher’s exact test). (XLSX 4875 kb)