Antimicrobial and hemolytic values of the peptides.

aMinimum inhibitory concentrations (MIC) were determined as the lowest concentration of the peptides that inhibited bacteria growth. The tests were performed at least three times in duplicate.bP. aeruginosa variant 1 was obtained by step-wise culture with ciprofloxacin hydrochloride.cP. aeruginosa variant 2 was obtained by step-wise culture with gentamicin.dMHC is the minimum concentration that caused 5% hemolysis of human red blood cells (hRBC). When no 5% hemolysis was observed at 256 µM, a value of 512 µM was used to calculate the therapeutic index.eGM denotes the geometric mean of MIC values from all microbial strains in this table.fTherapeutic index (TI) is the ratio of the MHC to the geometric mean of MICs (GM). Larger values indicate greater cell selectivity.