The Cs2CO3–Catalyzed Reaction of 2‑Oxindoles with Enones for the Preparation of Indolin-3-Ones and Their Further Transformation
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The Cs2CO3-catalyzed reaction of 2-oxindoles with enones affords 2,2-disubstituted indolin-3-ones through domino “Michael addition–oxidation–ring-cleavage–C–N coupling” process. O2 acts as the sole oxidant to accomplish the oxidative process. The indolin-3-ones can be further transformed to pyridazine, azirdine-fused 3-oxindoles, 4-quinolone derivatives easily.
创建时间：
2016-11-29
