RNA-seq and MYC ChIP-seq in A673 Ewing sarcoma cells with RUVBL1 knockout

This dataset examined the effect of RUVBL1 knockout in A673 Ewing sarcoma cells. The gene expression profiling (RNA-seq) and the chromatin targeting of MYC (ChIP-seq) are reported. Cas9-expressing A673 cells were transduced with sgCtrl and sgRUVBL1. The total RNA was extracted using the RNeasy Mini Kit (74104, QIAGEN) and submitted for RNA-seq at Novogene (PE150, NovoSeq6000). The MYC antibody (13987S, Cell Signaling Technology) cautured genomic DNA was submitted for ChIP-seq at Novogene (PE150, NovaSeq6000).