We have previously reported that the expression of mitochondrial deacetylase SIRT3 is high in the slow oxidative muscle and that the expression of muscle SIRT3 level is increased by dietary restrictio
Hyperlipidemic state-associated perturbations in the network of factors controlling mitochondrial functions, i. e., morphogenesis machinery and metabolic sensor proteins, produce metabolic inflexibili
This is the Source Data underlying Figs. 1d, 2e, 4a, 5e, g, 6b, and Supplementary Figs. 1g, 2c, 7a of the Nature Communications Paper "Dietary fatty acids fine-tune Piezo1 mechanical response" Liqui
AMPK (5â²-AMP-activated protein kinase) is an energetic sensor for metabolic regulation and integration. Here, we employed CRISPR/Cas9 to generate non-activatable Ampkα knock-in (KI) mice with a mut
The regulation of metabolism in peripheral tissues is mediated by pathways that are under circadian control. a bidirectional relationship is evident between the circadian clock and hypoxia-inducible f
