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Silver Triflate and Palladium Acetate Co-catalyzed Reaction of N′-(2-Alkynylbenzylidene)hydrazide with N-Allyl Ynamide

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Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Silver_Triflate_and_Palladium_Acetate_Co_catalyzed_Reaction_of_i_N_i_2_Alkynylbenzylidene_hydrazide_with_i_N_i_Allyl_Ynamide/2518039
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A silver triflate and palladium acetate co-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide with N-allyl ynamide is described, which generates 2-amino-H-pyrazolo[5,1-a]isoquinolines in good to excellent yield. The transformation proceeds with high efficiency through 6-endo cyclization, [3 + 2] cycloaddition, 3,3-sigmatropic rearrangement, and aromatization.
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2016-02-20
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