Rapid Construction of Vinyl Indomorphans by Rhenium Catalysis
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https://figshare.com/articles/dataset/Rapid_Construction_of_Vinyl_Indomorphans_by_Rhenium_Catalysis/24582804
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资源简介:
Here,
an efficient route for accessing the vinylindomorphan skeleton
is achieved by rhenium(I) catalysis. This transformation involves
the condensation of indoles and alkyne-linked cyclohexanones, followed
by intramolecular annulation to build the [3.3.1] bicyclic structure.
This protocol complements the synthesis of the structurally complex
heterocycles bearing a vinyl indole moiety. In addition, the selected
products exhibited moderate cytotoxicity toward human A549 cells.
创建时间:
2023-11-17



