Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with allosteric compound STL232591
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Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with allosteric compound STL232591 Descriptor: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, 8-methoxy-1-(4-methoxyphenyl)-3-methyl-2-oxidanyl-[1]benzofuro[3,2-c]pyridine, ... Authors: Thomsen, M, Thieulin-Pardo, G, Neumann, L. Deposit date: 2023-05-12 Release date: 2023-08-30 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorg.Med.Chem.Lett., 94, 2023
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2023-05-12
